MINISTER OF OCEAN DEVELOPMENT (DR. MURLI MANOHAR JOSHI)
(a) Yes, Sir.
(b) The National Project on `Drugs from Sea` initiated in 1991 with 10
participating institutes has collected and evaluated more than 4000 samples out
of 1400 numbers of marine flora and fauna for their biological activity. Several of
these samples were found to exhibit mild to strong therapeutic activities like
antidiabetic, antidiarrhoeal, antihyperlipidaemic, etc from various fractions
derived therefrom. Three organisms or extracts were taken up for further
development. These are given below:
- CDR-134D-123 (Antidiabetic) - CDR-134D-125 (Antidiarrhoeal) - CU002/004 (Antihyperlipidaemic)
These three samples have shown activities in repeated collections
and were taken up for toxicity studies during the IX Five Year Plan. The rodent
toxicity has been completed on the above first two preparations and these were
found safe. These toxicity studies have now been initiated in monkeys. The
toxicity of the third preparation has been started in July 2001.
(c) The total amount on the programme spent during 1990-2001 is
Rs.18.74 crores and for the year 2001-2002, Rs.2.19 crores is provided.
(d) & (e) Drug development takes 8-12 years and commercialization is done
after toxicity studies are over. In this case, the toxicity studies are currently
underway.