(a) whether Cyclotron is used for production of radio isotope used for diagnostic and medical use in cancer and if so, the types of cancer in these radio isotopes are used;
(b) whether cyclotron-30, the largest cyclotron for medical use in the country became operational this year; and
(c) if so, the cost of its research and manufacturing?
THE MINISTER OF STATE FOR PERSONNEL, PUBLIC GRIEVANCES & PENSIONS AND PRIME MINISTER’S OFFICE (Dr. JITENDRA SINGH):
(a) Yes, Sir. The radio-isotopes such as FDG (18F), Gallium (67Ga), Thallium (201Tl), Palladium (103Pd), Iodine (123I) are used for preparation of various radiopharmaceuticals, which are used for diagnostics and cancer therapy, as detailed below:-
i) 18F tracers for various diagnostic purposes
Radiopharmaceuticals Usages
[18F]Fluro-2-deoxygluclose Oncology, Neuro
[18F]Fluoride (Na18F) Bone Metastasis
[18F]Fluorothymidine Brain tumor, Osteosarcoma
2-[18F]Fluorotyrosine Cellualar aminoacid transport tumor
[18F]Fluorocholine Prostate carcinoma, soft tissue metastases
[18F]FMIZO/[18F] FAZA Hypoxia, therapy planning
[18F]Fluoroestradiol Hormone receptor status in breast cancer
[18F] FD OPA NETs and pancreatic b cell hyperplasia
ii) Other important radioisotopes for diagnostic and therapeutic uses
Gallium-67: Gallium-67 scintigraphy may include regional, whole-body, planar, and single photon emission computed tomography (SPECT) scintigrams, or any combination performed after intravenous injection of 67Ga-citrate for Soft tissue tumor imaging.
Thallium-201: Thallium-201 Chloride is a radiopharmaceutical used in myocardial perfusion imaging (MPI) using either planar or single photon emission computed tomography (SPECT) techniques for the diagnosis and localization of myocardial infarction.
Paladium-103: Prostate cancer therapy
Iodine-123: Single photon emission computed tomography (SPECT) for thyroid cancer imaging and detection of primary or metastatic pheochromocytoma
(b)&(c) Yes, Sir. The total cost of complete cyclotron systems is Rs. 156.22 crore.
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